Malaysian Red Crescent started providing Emergency Ambulance Services in May 1969 after taking over the 999 emergency assistance hotline from the Kuala Lumpur General Hospital. The service, launched on 4 June 1969, was formulated with an agreement between the government and MRC, with co-operation from the Ministry of Unity and Social Development, and the Ministry of Health. Over time, the service standard had improved and MRC currently provides full-time ambulance service to the public for emergencies, accidents and injuries.

At the National Headquarters, MRC has a fleet of 12 ambulances that operate with the support of 34 ambulance medical aides (AMA) and 6 emergency service officers (ESO).

From 2010, MRC has assisted more than 35,000 people who required medical aid during accidents, childbirth, natural disasters and other emergencies.

MRC also offers ambulance standby services for patient transfers, public gatherings, family days, sports events, exhibitions, concerts and more at a reasonable rate. The National Headquarters can be contacted for more information on these services. The ambulance service is also provided at the following states: Johor, Melaka, Selangor, Perak, Pahang, Terengganu, Penang, Kedah, Perlis, Sabah and Sarawak.